Domingo-Salvany A, Hartnoll R L, Maguire A, Suelves J M, Antó J M
Department of Epidemiology and Public Health, Universitat Autònoma de Barcelona, Spain.
Am J Epidemiol. 1995 Mar 15;141(6):567-74. doi: 10.1093/oxfordjournals.aje.a117472.
It is difficult to obtain accurate prevalence estimates of opiate addiction with direct methods. The capture-recapture method has been used to estimate the prevalence of hidden populations, including opiate addicts. In this study, we applied capture-recapture, including log-linear modeling, to estimate the prevalence of opiate addicts in Barcelona, Spain. Anonymous identification data from three 1989 sources (hospital emergency rooms, treatment admissions, and heroin overdose deaths) in Barcelona were used to obtain population samples. For prevalence estimation, two strategies were followed: 1) emergency room data only, divided into trimesters; and 2) all three sources used simultaneously. Estimates based only on emergency room data were lower than estimates obtained by the simultaneous analysis of all three data sources; the latter estimates gave narrower confidence intervals (6,324-7,414 addicts), giving a prevalence for Barcelona in 1989 of between 8.5 and 9.9 opiate addicts per 1,000 residents aged 15-44 years. The estimated prevalence varied by sex and age group and was highest in males aged 15-29 years (between 17.1 and 21.2). At least 42% had contacted one or more of the services studied, although only one in seven had been admitted for treatment during 1989. Capture-recapture is the election method for prevalence estimation when direct methods are not feasible.
用直接方法很难获得阿片类药物成瘾的准确患病率估计值。捕获再捕获法已被用于估计包括阿片类药物成瘾者在内的隐性人群的患病率。在本研究中,我们应用捕获再捕获法,包括对数线性模型,来估计西班牙巴塞罗那阿片类药物成瘾者的患病率。利用来自巴塞罗那1989年三个来源(医院急诊室、治疗入院和海洛因过量死亡)的匿名识别数据来获取人群样本。为了进行患病率估计,采用了两种策略:1)仅使用急诊室数据,按季度划分;2)同时使用所有三个来源的数据。仅基于急诊室数据的估计值低于对所有三个数据源同时进行分析所获得的估计值;后者的估计值给出的置信区间更窄(6324 - 7414名成瘾者),得出1989年巴塞罗那每1000名15 - 44岁居民中阿片类药物成瘾者的患病率在8.5至9.9之间。估计的患病率因性别和年龄组而异,在15 - 29岁男性中最高(在17.1至21.2之间)。至少42%的人曾接触过一项或多项所研究的服务,尽管在1989年只有七分之一的人被收治接受治疗。当直接方法不可行时,捕获再捕获法是患病率估计的首选方法。