胆汁会促进结肠外癌症吗？

Lancet. 1978 Jul 29;2(8083):239-41. doi: 10.1016/s0140-6736(78)91748-8.

The incidence of biliary-tract cancer and of several other gastrointestinal tumours is increased when conditions favour conversion of bile acids to more active substances. This may indicate that bacterial degradation of bile salts is related to the pathogenesis of cancer in parts of the alimentary tract other than the large bowel.

当条件有利于胆汁酸转化为更具活性的物质时，胆管癌和其他几种胃肠道肿瘤的发病率会升高。这可能表明胆盐的细菌降解与大肠以外的消化道部分癌症的发病机制有关。