Olsaker I, Mejdell C M, Sørensen A, Lie O
Department of Morphology, Genetics and Aquatic Biology, Norwegian College of Veterinary Medicine, Oslo.
Anim Genet. 1993 Dec;24(6):421-5. doi: 10.1111/j.1365-2052.1993.tb00355.x.
Analysis of restriction fragment length polymorphism (RFLP) of the lysozyme gene cluster was performed in a Norwegian bovine family segregating a single dominant Mendelian factor for high lysozyme activity in serum. An RFLP site with allelic bands of 16kb and 5.9 kb turned out to be linked to the locus for the high lysozyme activity factor with a lod score of 6.8 at a recombination fraction of 3.4%. This implies that we have revealed a genetic marker for the high lysozyme activity trait.
在一个挪威牛家族中进行了溶菌酶基因簇的限制性片段长度多态性(RFLP)分析,该家族中血清溶菌酶活性的单一显性孟德尔因子呈分离状态。一个等位基因带分别为16kb和5.9kb的RFLP位点,结果显示与高溶菌酶活性因子的基因座相连,在重组率为3.4%时,优势对数(lod)分数为6.8。这意味着我们已经揭示了高溶菌酶活性性状的一个遗传标记。