对一种新型抗风湿化合物酮洛芬（19.583 R.P.）对人体胃黏膜影响的胃镜评估。与阿司匹林进行双盲交叉试验。
Gastroscopic evaluation of the effect of a new anti-rheumatic compound, ketoprofen (19.583 R.P.), on the human gastric mucosa. A double-blind cross-over trial against acetylsalicylic acid.
作者信息
Rahbek I
出版信息
Scand J Rheumatol Suppl. 1976;1976(0):63-72.
The tolerance of the gastric mucosa to a new anti-inflammatory product, ketoprofen (19.583 R.P., Orudis, Profenid N.D.) was compared to the tolerance of acetylsalicylic acid in a double-blind cross-over trial using selected healthy volunteers. The effect of the medication on the gastric mucosa was examined by the use of a gastrocamera technique. The volunteers received during 2 one-week periods either acetylsalicylic acid 3 g daily or ketoprofen 100 mg daily. The sequential diagram shows that the upper barrier was crossed (preference for ketoprofen) when 10 volunteers had been analysed.
在一项双盲交叉试验中，使用选定的健康志愿者，将胃黏膜对一种新的抗炎产品酮洛芬（19.583 R.P.，奥鲁地，萘普生）的耐受性与乙酰水杨酸的耐受性进行了比较。通过使用胃内摄像技术检查药物对胃黏膜的影响。志愿者在两个为期一周的时间段内，分别每日服用3克乙酰水杨酸或100毫克酮洛芬。序列图显示，在分析了10名志愿者后，越过了上限（对酮洛芬更有利）。
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