Begg A C
Division of Experimental Therapy, The Netherlands Cancer Institute, Amsterdam.
Int J Radiat Biol. 1994 Jan;65(1):103-8. doi: 10.1080/09553009414550141.
An accurate prediction of response to radiotherapy would allow treatments to be modified for those individuals where a relatively poor response is expected with conventional treatment. Present assays receiving most attention are those for repopulation, radiosensitivity and hypoxia. This paper discusses our experience with the first two, together with relevant data from other groups. Attention is focussed particularly on correlations with outcome in clinical trials, and the accuracy of present assay methods.
准确预测放疗反应将使针对那些预计对传统治疗反应相对较差的个体调整治疗方案成为可能。目前最受关注的检测方法是关于再增殖、放射敏感性和缺氧情况的检测。本文讨论了我们在前两项检测方面的经验，以及其他研究小组的相关数据。特别关注与临床试验结果的相关性以及当前检测方法的准确性。
