Thompson I M, Lauvetz R
Urology. 1976 Nov;8(5):452-4. doi: 10.1016/0090-4295(76)90273-9.
Oxybutynin chloride (Ditropan), a tertiary amine possessing anticholinergic and papaverine-like, direct muscular antispasmodic effects, has been used in controlled clinical studies in patients with neurovesical reflex activity, uninhibited bladders, enuresis, and primary muscle spasm. The cystometrically documented, synergistic, anticholinergic, and muscle relaxant activity of oxybutynin observed in these studies indicates that the drug can be highly effective in the management of reflex neurovesical dysfunction, enuresis, and bladder spasm.
氯化奥昔布宁（得妥）是一种叔胺，具有抗胆碱能和类似罂粟碱的直接肌肉解痉作用，已用于对神经膀胱反射活动、无抑制膀胱、遗尿和原发性肌肉痉挛患者的对照临床研究。在这些研究中观察到的经膀胱测压记录的奥昔布宁的协同抗胆碱能和肌肉松弛活性表明，该药物在治疗反射性神经膀胱功能障碍、遗尿和膀胱痉挛方面可能非常有效。
