Beĭer E V
Eksp Klin Farmakol. 1994 Jan-Feb;57(1):20-1.
A chronobiological evaluation of the forced swimming test in rats treated with propranolol has shown that beta-adrenoblockers have antidepressive properties. This is true for oxprenolol which shows less pronounced affects. Nadolol that does not readily cross the blood-brain barrier insignificantly changes swimming behavior in the animals.
对用普萘洛尔治疗的大鼠进行强迫游泳试验的时间生物学评估表明,β-肾上腺素能阻滞剂具有抗抑郁特性。氧烯洛尔也是如此,其作用不太明显。不易透过血脑屏障的纳多洛尔对动物的游泳行为影响不大。