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[不同β-肾上腺素能阻滞剂抗抑郁活性的比较评估]

[A comparative evaluation of the antidepressive activity of different beta-adrenoblockaders].

作者信息

Beĭer E V

出版信息

Eksp Klin Farmakol. 1994 Jan-Feb;57(1):20-1.

PMID:7908240
Abstract

A chronobiological evaluation of the forced swimming test in rats treated with propranolol has shown that beta-adrenoblockers have antidepressive properties. This is true for oxprenolol which shows less pronounced affects. Nadolol that does not readily cross the blood-brain barrier insignificantly changes swimming behavior in the animals.

摘要

对用普萘洛尔治疗的大鼠进行强迫游泳试验的时间生物学评估表明,β-肾上腺素能阻滞剂具有抗抑郁特性。氧烯洛尔也是如此,其作用不太明显。不易透过血脑屏障的纳多洛尔对动物的游泳行为影响不大。

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引用本文的文献

1
Are Noradrenergic Transmission Reducing Drugs Antidepressants?去甲肾上腺素能传递减少药物是抗抑郁药吗?
Front Behav Neurosci. 2021 Sep 30;15:673634. doi: 10.3389/fnbeh.2021.673634. eCollection 2021.