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乳腺癌患者中乳腺癌的部分和完全消退与辅酶Q10剂量的关系

Partial and complete regression of breast cancer in patients in relation to dosage of coenzyme Q10.

作者信息

Lockwood K, Moesgaard S, Folkers K

机构信息

Pharma Nord, Vejle, Denmark.

出版信息

Biochem Biophys Res Commun. 1994 Mar 30;199(3):1504-8. doi: 10.1006/bbrc.1994.1401.

DOI:10.1006/bbrc.1994.1401
PMID:7908519
Abstract

Relationships of nutrition and vitamins to the genesis and prevention of cancer are increasingly evident. In a clinical protocol, 32 patients having -"high-risk"- breast cancer were treated with antioxidants, fatty acids, and 90 mg. of CoQ10. Six of the 32 patients showed partial tumor regression. In one of these 6 cases, the dosage of CoQ10 was increased to 390 mg. In one month, the tumor was no longer palpable and in another month, mammography confirmed the absence of tumor. Encouraged, another case having a verified breast tumor, after non-radical surgery and with verified residual tumor in the tumor bed was then treated with 300 mg. CoQ10. After 3 months, the patient was in excellent clinical condition and there was no residual tumor tissue. The bioenergetic activity of CoQ10, expressed as hematological or immunological activity, may be the dominant but not the sole molecular mechanism causing the regression of breast cancer.

摘要

营养和维生素与癌症发生及预防之间的关系日益明显。在一项临床方案中,32例患有“高危”乳腺癌的患者接受了抗氧化剂、脂肪酸和90毫克辅酶Q10的治疗。32例患者中有6例出现部分肿瘤消退。在这6例中的1例中,辅酶Q10的剂量增加到390毫克。1个月后,肿瘤不再可触及,再过1个月,乳房X光检查证实肿瘤消失。受此鼓舞,另一例经证实患有乳腺肿瘤的患者,在进行非根治性手术后且肿瘤床有残留肿瘤,随后接受了300毫克辅酶Q10的治疗。3个月后,患者临床状况良好,且无残留肿瘤组织。辅酶Q10的生物能量活性,以血液学或免疫学活性表示,可能是导致乳腺癌消退的主要但非唯一分子机制。

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