On the metabolic characteristic of hybrids Shigella flexneri x Escherichia coli devoid of their ability for intracellular multiplication in the epithelial cells. II. Catalase and phosphatase activity.

The catalase and phosphatase activity of avirulent by keratoconjunctival test of guinea pigs xyl+ and xyl-str (KCP-) hybrids that have lost their ability for intracellular multiplication, received from virulent strains. Sh. flexneri (Sh. flexneri 222 5 a and Sh. flexneri M42-43) and donor strain E. coli AB 313 was investigated. It is established that there is a definite dependence between the changes in the catalase and the phosphatase activities of the hybrid strains and the newly received by the hybridization genetic information. The enzyme activity of the hybrid strains always correlated with the level of this activity in the donor strains E. coli.