Radoutcheva T, Veljanov D, Popov C, Bondarendo V M
Zentralbl Bakteriol Orig A. 1975 Oct;233(2):223-7.
The catalase and phosphatase activity of avirulent by keratoconjunctival test of guinea pigs lac+, kcp- hybrids that have lost their ability of penetrating in the epithelium, received from virulent strains Shigella flexneri (Sh. flexneri 222 5a and Sh. flexneri M42-43) and donor strains Escherichia coli (E. coli K-12, P4x and E. coli H) was investigated. It was established that there is no any dependence between the lost of virulence of the hybrids and the level of the catalase activity. During the study of the phosphatase activity it was established, that in comparison with the recipient virulent shigella strains, the investigated avirulent lac+-hybrids revealed higher values of the enzyme activity.
对豚鼠角膜结膜试验无毒的lac +、kcp -杂种进行了过氧化氢酶和磷酸酶活性研究，这些杂种失去了在上皮细胞中穿透的能力，它们源自弗氏志贺氏菌（弗氏志贺氏菌222 5a和弗氏志贺氏菌M42 - 43）的有毒菌株以及供体菌株大肠杆菌（大肠杆菌K - 12、P4x和大肠杆菌H）。结果表明，杂种毒力的丧失与过氧化氢酶活性水平之间不存在任何相关性。在研究磷酸酶活性时发现，与受体有毒志贺氏菌菌株相比，所研究的无毒lac +杂种显示出更高的酶活性值。
