Zimmerman D R, Collins T M, Lipowski E E, Sainfort F
Center for Health Systems Research and Analysis, University of Wisconsin-Madison 53705.
Inquiry. 1994 Spring;31(1):89-101.
Drug Utilization Review (DUR) programs aim to control inappropriate prescribing and drug costs, but there are few rigorous studies of their impact. This paper presents the evaluation results of a DUR intervention (excessive duration of full-dose histamine-2 receptor antagonists) using a quasi-experimental design. We observe a greater reduction of H2RA use in the intervention group than in the comparison group, and a reduction in drug expenditures which exceeded the cost of targeting and notifying prescribers. The success of DUR programs depends on both their efficiency and the drug issues under consideration; the use of a comparison group is critical in the evaluation of their impact.
药物利用审查（DUR）项目旨在控制不适当的处方行为和药物成本，但对其影响进行严格研究的却很少。本文采用准实验设计，呈现了一项DUR干预措施（全剂量组胺-2受体拮抗剂使用时间过长）的评估结果。我们观察到，干预组中H2RA的使用减少幅度大于对照组，且药物支出有所减少，这一减少幅度超过了针对和通知开处方者的成本。DUR项目的成功取决于其效率以及所考虑的药物问题；在评估其影响时，使用对照组至关重要。
