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Health Serv Res. 1999 Feb;33(6):1593-610.
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[Helicobacter pylori eradication in ulcer patients. Quality of life improves, costs decline].[溃疡患者根除幽门螺杆菌。生活质量提高,成本下降]
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Cochrane Database Syst Rev. 2015 May 8;2015(5):CD007017. doi: 10.1002/14651858.CD007017.pub2.
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本文引用的文献

1
A critical analysis of studies of state drug reimbursement policies: research in need of discipline.对国家药品报销政策研究的批判性分析:亟需规范的研究。
Milbank Q. 1993;71(2):217-52.
2
Effects of a limiting Medicaid drug-reimbursement benefits on the use of psychotropic agents and acute mental health services by patients with schizophrenia.医疗补助药物报销福利受限对精神分裂症患者使用精神药物及急性心理健康服务的影响。
N Engl J Med. 1994 Sep 8;331(10):650-5. doi: 10.1056/NEJM199409083311006.
3
Evaluation of a DUR intervention: a case study of histamine antagonists.药物利用审查干预措施的评估:组胺拮抗剂的案例研究
Inquiry. 1994 Spring;31(1):89-101.
4
Pharmacists' reactions to the Wisconsin Medicaid drug-use review program.药剂师对威斯康星医疗补助药品使用审查计划的反应。
Am J Hosp Pharm. 1993 Sep;50(9):1898-902.
5
Cimetidine and perforated peptic ulcer.西咪替丁与穿孔性消化性溃疡
Br J Surg. 1982 Jun;69(6):319-20. doi: 10.1002/bjs.1800690609.
6
Antacids for peptic ulcer: do we have anything better?用于消化性溃疡的抗酸剂:我们有更好的药物吗?
Scand J Gastroenterol Suppl. 1986;125:32-41. doi: 10.3109/00365528609093815.
7
Payment restrictions for prescription drugs under Medicaid. Effects on therapy, cost, and equity.医疗补助计划下处方药的支付限制。对治疗、成本和公平性的影响。
N Engl J Med. 1987 Aug 27;317(9):550-6. doi: 10.1056/NEJM198708273170906.
8
Incidence of perforated and bleeding peptic ulcers before and after the introduction of H2-receptor antagonists.H2受体拮抗剂应用前后消化性溃疡穿孔和出血的发生率
Ann Surg. 1988 Jan;207(1):4-6. doi: 10.1097/00000658-198801000-00002.
9
Double-blind randomized multicenter study comparing Maalox TC tablets and ranitidine in healing of duodenal ulcers.
Dig Dis Sci. 1991 Jul;36(7):911-6. doi: 10.1007/BF01297140.
10
Effects of Medicaid drug-payment limits on admission to hospitals and nursing homes.医疗补助药品支付限额对医院和疗养院入院情况的影响。
N Engl J Med. 1991 Oct 10;325(15):1072-7. doi: 10.1056/NEJM199110103251505.

对抗溃疡药物报销的限制能否在不增加住院率的情况下降低医疗补助计划的药房成本?

Can restrictions on reimbursement for anti-ulcer drugs decrease Medicaid pharmacy costs without increasing hospitalizations?

作者信息

Cromwell D M, Bass E B, Steinberg E P, Yasui Y, Ravich W J, Hendrix T R, McLeod S F, Moore R D

机构信息

Department of Medicine, The Johns Hopkins University, Baltimore, MD 21205, USA.

出版信息

Health Serv Res. 1999 Feb;33(6):1593-610.

PMID:10029499
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1070338/
Abstract

OBJECTIVE

To examine the impact of a policy restricting reimbursement for Medicaid anti-ulcer drugs on anti-ulcer drug use and peptic-related hospitalizations.

DATA SOURCES/STUDY SETTING: In addition to U.S. Census Bureau data, all of the following from Florida: Medicaid anti-ulcer drug claims data, 1989-1993; Medicaid eligibility data, 1989-1993; and acute care nonfederal hospital discharge abstract data (Medicaid and non-Medicaid), 1989-1993.

STUDY DESIGN

In this observational study, a Poisson multiple regression model was used to compare changes, after policy implementation, in Medicaid reimbursement for prescription anti-ulcer drugs as well as hospitalization rates between pre- and post-implementation periods in Medicaid versus non-Medicaid patients hospitalized with peptic ulcer disease.

PRINCIPAL FINDINGS

Following policy implementation, the rate of Medicaid reimbursement for anti-ulcer drugs decreased 33 percent (p < .001). No associated increase occurred in the rate of Medicaid peptic-related hospitalizations.

CONCLUSIONS

Florida's policy restricting Medicaid reimbursement for anti-ulcer drugs was associated with a substantial reduction in outpatient anti-ulcer drug utilization without any significant increase in the rate of hospitalization for peptic-related conditions.

摘要

目的

研究一项限制医疗补助计划(Medicaid)抗溃疡药物报销政策对该类药物使用及消化性溃疡相关住院情况的影响。

数据来源/研究背景:除美国人口普查局数据外,还使用了来自佛罗里达州的以下所有数据:1989 - 1993年医疗补助计划抗溃疡药物报销申请数据;1989 - 1993年医疗补助计划资格数据;以及1989 - 1993年急性护理非联邦医院出院摘要数据(包括医疗补助和非医疗补助患者)。

研究设计

在这项观察性研究中,采用泊松多元回归模型,比较政策实施后,医疗补助计划中处方抗溃疡药物报销情况的变化,以及患有消化性溃疡疾病的医疗补助患者与非医疗补助患者在政策实施前后的住院率变化。

主要发现

政策实施后,医疗补助计划中抗溃疡药物的报销率下降了33%(p <.001)。与消化性溃疡相关的医疗补助住院率没有相应增加。

结论

佛罗里达州限制医疗补助计划抗溃疡药物报销的政策,与门诊抗溃疡药物使用率大幅下降相关,而消化性溃疡相关疾病的住院率没有显著上升。