Eichhorn E J
Department of Medicine, University of Texas Southwestern Medical Center, Dallas.
Cardiol Clin. 1994 Feb;12(1):133-42.
beta-adrenergic blocking agents have been demonstrated to benefit ventricular systolic and diastolic function, improve functional class, and reduce neurohormonal activation in patients with congestive heart failure. Their effects on mortality, although still unknown, are unlikely to be adverse and more likely to be favorable based on prior studies. Future studies of the effect of beta-adrenergic blockade on survival are warranted. These agents are slowly gaining acceptance as a novel treatment modality for patients who have congestive heart failure.
β-肾上腺素能阻滞剂已被证明可改善充血性心力衰竭患者的心室收缩和舒张功能，提高心功能分级，并减少神经激素激活。尽管其对死亡率的影响尚不清楚，但根据先前的研究，不太可能产生不良影响，更有可能是有益的。有必要对β-肾上腺素能阻滞剂对生存率的影响进行进一步研究。这些药物正逐渐被接受为充血性心力衰竭患者的一种新型治疗方式。
