在二价阳离子离子载体A23187诱导的细胞融合过程中，母鸡红细胞膜内颗粒分布的变化
Changes in the distribution of intramembranous particles in hen erythrocytes during cell fusion induced by the bivalent-cation ionophore A23187.
作者信息
Vos J, Ahkong Q F, Botham G M, Quirk S J, Lucy J A
出版信息
Biochem J. 1976 Sep 15;158(3):651-3. doi: 10.1042/bj1580651.
Abstract
Incubation of hen erythrocytes with Ca2+ and the bivalent-cation ionophore A23187 induced slight cell fusion in 1 h at 37 degrees C, and extensive fusion during a subsequent 15 min at 47 degrees C. Redistributions of intramembranous particles were observed, possibly involving interactions between Ca2+ and phospholipids, which are discussed in relation to molecular mechanimss of cell fusion.
摘要
将鸡红细胞与钙离子及二价阳离子载体A23187一起孵育，在37℃下1小时会诱导轻微的细胞融合，随后在47℃下15分钟内会发生广泛融合。观察到膜内颗粒的重新分布，这可能涉及钙离子与磷脂之间的相互作用，本文将结合细胞融合的分子机制进行讨论。
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