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[预防艾滋病患者机会性鸟分枝杆菌感染的利害关系。采自对帕特里克·菲利贝尔特医生的访谈]

[The stakes in preventing opportunistic MAI infections in AIDS. From an interview with Dr. Patrick Philibert].

作者信息

Philibert P

出版信息

Allerg Immunol (Paris). 1994 Apr;26(4):145-8.

PMID:7913323
Abstract

Development of HIV infection is littered with many pathological episodes of which the physical and psychological repercussions on the patient are full of consequences. In this context, full co-operation between the hospital services and general practitioners is fundamental, from the moment of the announcement of seropositivity, to place under anti-retroviral treatment and to follow the pathological events. Opportunistic infections that threaten the life of the patient are severe because of the fall in the level of CD4 lymphocytes. Nowadays it is important to start prophylactic treatments and to make the patient understand the fight to follow these treatments that alone can help to maintain his autonomy and quality of life. The quality of the relationship established between the practitioner and patient is here very important. At the start of prophylactic treatment for several opportunistic infections in AIDS, such as pneumocystosis or toxoplasmosis, it is essential to have available an effective therapeutic strategy for infection by Mycobacterium avium complex (MAC). In effect, these serious infections following after the development of AIDS, graviously threaten the life of patients and their probability to survive. Today, practitioners have available rifabutine (Ansatipine) which is an efficacious treatment for MAC infections. It is sure that many patients will find benefit.

摘要

HIV感染的发展过程充斥着许多病理阶段,这对患者的生理和心理都会产生诸多影响。在这种情况下,从宣布血清反应阳性的那一刻起,医院服务部门和全科医生之间的充分合作至关重要,以便对患者进行抗逆转录病毒治疗并跟踪病理情况。由于CD4淋巴细胞水平下降,威胁患者生命的机会性感染非常严重。如今,开始预防性治疗并让患者明白坚持这些治疗的重要性非常重要,只有这样才能帮助维持其自主性和生活质量。从业者与患者之间建立的关系质量在此非常重要。在开始针对艾滋病患者的几种机会性感染(如肺孢子菌病或弓形虫病)进行预防性治疗时,必须有针对鸟分枝杆菌复合群(MAC)感染的有效治疗策略。实际上,这些在艾滋病发展后出现的严重感染严重威胁着患者的生命及其生存几率。如今,从业者可以使用利福布汀(安莎平),它是治疗MAC感染的有效药物。可以肯定的是,许多患者将从中受益。

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Rifabutin prophylaxis against Mycobacterium avium complex infection.利福布汀预防鸟分枝杆菌复合群感染。
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