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逆行信号传导与无脊椎动物神经系统中递质释放特性的发育

Retrograde signaling and the development of transmitter release properties in the invertebrate nervous system.

作者信息

Davis G W, Murphey R K

机构信息

Biology Department, Morrill Science Center (South), University of Massachusetts, Amherst 01003.

出版信息

J Neurobiol. 1994 Jun;25(6):740-56. doi: 10.1002/neu.480250612.

DOI:10.1002/neu.480250612
PMID:7915302
Abstract

The dynamics of presynaptic transmitter release are often matched to the functional properties of the postsynaptic cell. In organisms ranging from cats to crickets, evidence suggests that retrograde signaling is essential for matching these presynaptic release properties to individual postsynaptic partners. Retrograde interactions appear to control the development of presynaptic, short-term facilitation and depression.

摘要

突触前递质释放的动力学通常与突触后细胞的功能特性相匹配。从猫到蟋蟀等生物中，有证据表明逆行信号传导对于使这些突触前释放特性与单个突触后伙伴相匹配至关重要。逆行相互作用似乎控制着突触前短期易化和抑制的发展。

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