Hoffstein V
Department of Medicine, St Michael's Hospital, Toronto, Ontario, Canada.
Lancet. 1994 Sep 3;344(8923):643-5. doi: 10.1016/s0140-6736(94)92084-2.
The association between snoring and blood pressure is still a matter for debate, partly because of uncertainty about the definition of snoring and partly because confounding factors may affect systemic blood pressure such as obesity, sleep apnoea, and nocturnal hypoxaemia. To isolate the contribution of each of these factors, 1415 patients (389 females, 1026 males) referred to a sleep disorders centre were studied. A full history was obtained with particular attention to cardiovascular disease and medications. The patients had nocturnal polysomnography including objective measurement of snoring, and blood pressure was measured in the morning. 18% of non-snores had hypertension as did 20% of heavy snores (not significantly different). Multivariate linear regression analysis showed that snoring was not a significant determinant of blood pressure. Only age, male sex, apnoea/hypopnoea index, and body mass index contributed significantly to the variability of blood pressure. We conclude that snoring in the absence of sleep apnoea is not associated with raised blood pressure.
打鼾与血压之间的关联仍是一个有争议的问题，部分原因是打鼾的定义尚不确定，部分原因是诸如肥胖、睡眠呼吸暂停和夜间低氧血症等混杂因素可能会影响全身血压。为了分离出这些因素各自的影响，我们对转诊至睡眠障碍中心的1415名患者（389名女性，1026名男性）进行了研究。获取了详细的病史，特别关注心血管疾病和用药情况。患者接受了夜间多导睡眠监测，包括对打鼾进行客观测量，并在早晨测量血压。18%的不打鼾者患有高血压，重度打鼾者中这一比例为20%（无显著差异）。多变量线性回归分析表明，打鼾不是血压的显著决定因素。只有年龄、男性性别、呼吸暂停/低通气指数和体重指数对血压的变异性有显著影响。我们得出结论，在没有睡眠呼吸暂停的情况下，打鼾与血压升高无关。
