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打鼾者和对照组中的周期性呼吸与缺氧:打鼾病史的验证及其与血压和肥胖的关联

Periodic breathing and hypoxia in snorers and controls: validation of snoring history and association with blood pressure and obesity.

作者信息

Telakivi T, Partinen M, Koskenvuo M, Salmi T, Kaprio J

出版信息

Acta Neurol Scand. 1987 Jul;76(1):69-75. doi: 10.1111/j.1600-0404.1987.tb03547.x.

DOI:10.1111/j.1600-0404.1987.tb03547.x
PMID:3630648
Abstract

Fifty-two men (aged 41-50 years) of whom 25 reported habitual and 27 of occasional or never snoring were examined clinically. Whole-night sleep recordings of body and breathing movements, snoring and blood oxygen saturation were made. Hypoxic events exceeding 4% from the baseline were counted. Ninety-three percent of those classified snorers by the recordings were habitual or occasional snorers, but 50% of those similarly classified non-snorers had reported habitual or occasional snoring. Four habitual snorers had abnormal breathing indices and polysomnography established obstructive sleep apnea syndrome (OSAS) in one. Thus, self-reported habitual snoring is a reliable OSAS-screening method. Estimated prevalence of OSAS based on this study is 0.4-1.4%. In multivariate regression analysis, the hypoxic events were explained by obesity and apneic events. The diastolic blood pressure level was best explained by obesity, but not hypoxic or apneic events or snoring history.

摘要

对52名年龄在41至50岁之间的男性进行了临床检查,其中25人自述有习惯性打鼾,27人偶尔打鼾或从不打鼾。记录了整夜的身体和呼吸运动、打鼾情况及血氧饱和度。统计了血氧饱和度较基线下降超过4%的缺氧事件。记录显示,93%被归类为打鼾者的人是习惯性或偶尔打鼾者,但同样被归类为非打鼾者的人中,有50%自述有习惯性或偶尔打鼾。4名习惯性打鼾者呼吸指数异常,多导睡眠图检查确诊其中1人患有阻塞性睡眠呼吸暂停综合征(OSAS)。因此,自我报告的习惯性打鼾是一种可靠的OSAS筛查方法。基于本研究估计的OSAS患病率为0.4%-1.4%。在多变量回归分析中,缺氧事件可由肥胖和呼吸暂停事件解释。舒张压水平最好由肥胖解释,而非缺氧、呼吸暂停事件或打鼾史。

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