Lin M T, Yang P C, Luh K T
Department of Internal Medicine, Chang-Hua Christian Hospital, Taiwan, R.O.C.
J Formos Med Assoc. 1994 Mar;93(3):250-2.
Malignant pericardial effusion with cardiac tamponade is a life-threatening oncological emergency. Pericardiocentesis with sclerosing therapy is a life-saving palliative treatment procedure. Because of the short life expectancy in these patients, pericardial constriction after pericardial sclerosing therapy has been rarely reported in the literature. We report a patient with malignant pericardial effusion and cardiac tamponade which was successfully controlled by intrapericardial mitomycin C instillation. This patient developed pericardial constriction six months after mitomycin C pericardial sclerosis. It should be noted that pericardial constriction may occur if a patient survives long enough after successful pericardial sclerosis.
恶性心包积液伴心脏压塞是一种危及生命的肿瘤急症。心包穿刺硬化治疗是一种挽救生命的姑息治疗方法。由于这些患者预期寿命较短，心包硬化治疗后发生心包缩窄在文献中鲜有报道。我们报告一例恶性心包积液伴心脏压塞患者，通过心包内注入丝裂霉素C成功控制病情。该患者在丝裂霉素C心包硬化治疗6个月后发生心包缩窄。需要注意的是，如果患者在心包硬化治疗成功后存活时间足够长，可能会发生心包缩窄。
