Tokoro K, Chiba Y, Abe H, Tanaka N, Yamataki A, Kanno H
Department of Neurosurgery, Kanagawa Rehabilitation Center, Japan.
Childs Nerv Syst. 1994 May;10(4):236-8. doi: 10.1007/BF00301160.
The effects of an anti-siphon device (ASD) on shunt flow and intracranial pressure (ICP) in 16 children with hypertensive hydrocephalus were examined using quantitative radionuclide shuntography (99mTc) with the children in supine and sitting positions. The average age of these patients was 9.5 years. Results were compared with those recorded in 36 patients with adult normal-pressure hydrocephalus (NPH). The closing pressure levels of shunt valve used were low in 8 cases, medium in 7 and high in 1. Half the children (8) had shunt systems with, and the other 8 without, ASD. In the children who had the shunt system without ASD, sitting shunt flow was significantly greater than supine shunt flow, which indicated overdrainage. Conversely, in children who had the shunt system with ASD, supine shunt flow was greater than sitting shunt flow. Because ASD prevented overdrainage, ICP was higher with the shunt system with ASD than with the shunt system without ASD. Without ASD, sitting shunt flow of children was lower than that of adult patients with NPH because of the lower hydrostatic pressure, which correlated with their height. Conversely, in the presence of a shunt system with ASD, sitting shunt flow of children was greater than that of adults, because of the higher ICP and lower hydrostatic pressure. The effect of ASD was smaller in children than in adults, because positive pressure over the ASD was greater (hypertension vs normal pressure) and negative pressure under the ASD was less (short vs tall) in children than in adults. Thus, in children the ASD was effective in preventing overdrainage.(ABSTRACT TRUNCATED AT 250 WORDS)
采用定量放射性核素分流造影术(99mTc),让16名患有高血压性脑积水的儿童分别处于仰卧位和坐位,研究抗虹吸装置(ASD)对分流流量和颅内压(ICP)的影响。这些患者的平均年龄为9.5岁。将结果与36名成人正常压力脑积水(NPH)患者的记录结果进行比较。所使用的分流阀关闭压力水平,8例为低水平,7例为中等水平,1例为高水平。一半儿童(8名)的分流系统有ASD,另外8名没有。在没有ASD的分流系统的儿童中,坐位分流流量明显大于仰卧位分流流量,这表明存在过度引流。相反,在有ASD的分流系统的儿童中,仰卧位分流流量大于坐位分流流量。由于ASD可防止过度引流,有ASD的分流系统的ICP高于没有ASD的分流系统。没有ASD时,儿童的坐位分流流量低于成人NPH患者,这是因为静水压较低,而静水压与他们的身高相关。相反,在有ASD的分流系统的情况下,儿童的坐位分流流量大于成人,这是因为ICP较高且静水压较低。ASD对儿童的影响小于对成人的影响,因为儿童ASD上方的正压更大(高血压与正常压力相比),ASD下方的负压更小(身材矮与身材高相比)。因此,在儿童中,ASD可有效防止过度引流。(摘要截选于250词)