Risk factors for hepatocellular carcinoma in Guangxi, People's Republic of China.

Fusui County in the Guangxi Autonomous Region of China is a high-risk area for hepatocellular carcinoma (HCC). In 1971-73, the average annual standardized (world population) mortality rate of HCC in Fusui was 20.09 and 111.75/100,000 person-years for females and males, respectively. Epidemiologic and pathologic studies of HCC have been conducted in Fusui since 1959. This paper describes some of the studies relating to the hepatitis B virus infection and aflatoxin contamination of foodstuffs.