Wu Q, Xu W, Chen Z
Institute of Acupuncture & Moxibustion, China Academy of Traditional Chinese Medicine, Beijing.
Zhen Ci Yan Jiu. 1993;18(3):205-8.
In order to confirm the idea that the cerebral cortex is involved in acupuncture analgesia through descending modulation, the effects of stimulation of SmI and electroacupuncture on nociceptive responses of VB neurons were investigated. The experiments were carried out on lightly anesthetized rats. Single unit activities of VB neurons were extracellularly recorded with glass microelectrodes. The results showed that both electrical stimulation of SmI (n = 11) and electroacupuncture at left. "Huantiao" (G30) point (n = 11) could inhibit the nociceptive responses of VB neurons and their effects were similar. These results suggested that SmI may play a role in acupuncture analgesia through corticofugal modulation on VB.
为了证实大脑皮层通过下行调制参与针刺镇痛这一观点，研究了刺激中央后回最下脚（SmI）和电针刺激对脊神经节（VB）神经元伤害性反应的影响。实验在轻度麻醉的大鼠上进行。用玻璃微电极细胞外记录VB神经元的单位活动。结果表明，刺激SmI（n = 11）和电针刺激左侧“环跳”（G30）穴（n = 11）均能抑制VB神经元的伤害性反应，且二者效果相似。这些结果提示，SmI可能通过对VB的皮质离心调制在针刺镇痛中发挥作用。
