van Rooij W J, Borstlap A C, Canta L R, Tijssen C C
Department of Neuroradiology, St. Elisabeth Hospital, Tilburg, The Netherlands.
Clin Neurol Neurosurg. 1994 May;96(2):181-4. doi: 10.1016/0303-8467(94)90059-0.
Two obese patients suffering from neurogenic claudication caused by lumbar epidural lipomatosis are described. Although lumbar epidural lipomatosis is most often related to prolonged use of steroid drugs, obesity has also been reported as a possible cause. Both CT and MRI can demonstrate excess epidural fat; because of the possibility of sagittal views MRI is to be preferred. In one of our patient with neurogenic claudication the excess epidural fat normalised completely after considerable weight reduction and symptoms resolved. Therefore weight reduction might be the initial therapy in an obese patient with symptomatic epidural lipomatosis. When weight reduction fails or when there are urgent clinical reasons, surgical removal of the excess amount of epidural fat should be considered.
本文描述了两名因腰椎硬膜外脂肪增多症导致神经源性间歇性跛行的肥胖患者。虽然腰椎硬膜外脂肪增多症最常与长期使用类固醇药物有关,但肥胖也被报道为可能的病因。CT和MRI都能显示硬膜外脂肪过多;由于MRI可以进行矢状位观察,因此更值得选用。在我们的一名神经源性间歇性跛行患者中,体重显著减轻后硬膜外脂肪过多的情况完全恢复正常,症状也得到缓解。因此,对于有症状的硬膜外脂肪增多症肥胖患者,减轻体重可能是初始治疗方法。当体重减轻无效或存在紧急临床原因时,应考虑手术切除多余的硬膜外脂肪。