Lisai P, Doria C, Crissantu L, Meloni G B, Conti M, Achene A
Department of Orthopaedic Surgery, University of Sassari, Italy.
Spine (Phila Pa 1976). 2001 Feb 1;26(3):307-9. doi: 10.1097/00007632-200102010-00017.
Three cases of idiopathic epidural lipomatosis are reported.
Description of the relationship between spinal pathologic overgrowth of fat tissue and neurologic symptoms.
Idiopathic epidural lipomatosis is a very rare condition; it is usually secondary to chronic steroid therapy or endocrinopathic diseases.
Three men with a mean age of 58.5 years, who experienced intermittent claudication, bilateral radicular pain in both legs, and urinary dysfunction with hypoesthesia in the perineal region, were evaluated by plain radiography and magnetic resonance imaging, the results of which demonstrated a pathologic overgrowth of fat tissue in the spinal canal with a marked impingement of the dural sac. Obesity, endocrinopathic diseases, and chronic steroid therapy were excluded for all patients. Surgical treatment was performed by wide multilevel laminectomies, fat debulking, and instrumented posterolateral fusion.
After surgery there was a gradual improvement in symptoms and signs so that 2 years later the patients returned to daily activities and were neurologically normal.
Spinal epidural lipomatosis can be a cause of back pain but rarely radicular impingement. Magnetic resonance imaging is the procedure of choice. The treatment must be performed early by wide surgical decompression.
报告3例特发性硬膜外脂肪增多症病例。
描述脂肪组织的脊柱病理性过度生长与神经症状之间的关系。
特发性硬膜外脂肪增多症是一种非常罕见的疾病;通常继发于慢性类固醇治疗或内分泌疾病。
对3名平均年龄58.5岁的男性进行评估,他们经历间歇性跛行、双侧腿部神经根性疼痛以及会阴区感觉减退伴排尿功能障碍,通过X线平片和磁共振成像进行检查,结果显示椎管内脂肪组织病理性过度生长,硬脊膜囊明显受压。所有患者均排除肥胖、内分泌疾病和慢性类固醇治疗史。通过广泛的多节段椎板切除术、脂肪减容和器械辅助后外侧融合术进行手术治疗。
术后症状和体征逐渐改善,2年后患者恢复日常活动,神经功能正常。
脊柱硬膜外脂肪增多症可能是背痛的原因,但很少导致神经根受压。磁共振成像是首选的检查方法。必须尽早通过广泛的手术减压进行治疗。