Pouchot J, Si-Hassen C, Damade R, Bayeux M C, Mathieu A, Vinceneux P
Department of Médecine Interne, Hôpital Louis Mourier, Université Paris VII, Colombes, France.
J Rheumatol. 1995 Sep;22(9):1771-5.
Epidural lipomatosis (EL) is characterized by abnormal accumulation of unencapsulated fat in the epidural space, and usually occurs as a complication of longterm steroid therapy. This condition, which may result in devastating neurologic complications, has also been reported without exogenous steroid intake. We describe a case of nonsteroid induced symptomatic EL associated with obesity, and emphasize the possibility of effective medical management of this entity with weight reduction instead of decompressive laminectomy whenever neurologic symptoms are mild and stable.
硬膜外脂肪增多症（EL）的特征是硬膜外间隙出现未被包裹的脂肪异常蓄积，通常作为长期类固醇治疗的并发症发生。这种情况可能导致严重的神经并发症，也有在未摄入外源性类固醇的情况下发生的报道。我们描述了一例与肥胖相关的非类固醇诱导的症状性EL病例，并强调当神经症状轻微且稳定时，通过减轻体重而非减压性椎板切除术对该病症进行有效药物治疗的可能性。
