Spector M
Department of Orthopedic Surgery, Harvard Medical School, Boston, Massachusetts.
Clin Plast Surg. 1994 Jul;21(3):437-44.
A number of approaches have directed toward the development of a substance that can substitute for allogeneic bone for grafting procedures. Synthetic HA ceramic materials are limited in being able to serve as analogs of bone mineral for use as implants to facilitate bone regeneration. HA ceramics do not replicate the chemistry and crystalline structure of natural bone mineral. An alternative approach has been to deorganify bovine bone to produce bone mineral in forms that can be employed as implants.
许多方法都致力于研发一种能够替代异体骨用于移植手术的物质。合成羟基磷灰石（HA）陶瓷材料作为骨矿物质的类似物用作植入物以促进骨再生时存在局限性。HA陶瓷无法复制天然骨矿物质的化学性质和晶体结构。另一种方法是去除牛骨中的有机成分，以生产可作为植入物使用的骨矿物质形式。
