Aboulafia D M, Bush R, Picozzi V J
Section of Hematology and Oncology, University of Washington, Seattle.
Chest. 1994 Oct;106(4):1295-9. doi: 10.1378/chest.106.4.1295.
Cardiac tamponade due to lymphomatous involvement of the heart is a dramatic and unusual complication. Because of their nonspecific clinical presentation, these tumors are seldom diagnosed antemortem. We report the case of a patient with AIDS who presented with signs and symptoms of cardiac tamponade. Emergency pericardiocentesis followed by staging studies revealed large cell B-lymphocyte lymphoma confined to the pericardial space. With combination chemotherapy, a durable complete response was obtained. This case illustrates the potential benefit of aggressive treatment of extranodal non-Hodgkin's lymphoma in a patient with AIDS. The case is of particular interest because of the unusual development of isolated pericardial involvement as the sentinel sign of lymphoma.
心脏受淋巴瘤侵犯导致的心包填塞是一种严重且罕见的并发症。由于其临床表现缺乏特异性，这些肿瘤生前很少被诊断出来。我们报告一例艾滋病患者出现心包填塞的症状和体征。紧急心包穿刺术及后续分期检查显示为局限于心包腔的大细胞B淋巴细胞淋巴瘤。通过联合化疗，患者获得了持久的完全缓解。该病例说明了积极治疗艾滋病患者结外非霍奇金淋巴瘤的潜在益处。由于孤立的心包受累作为淋巴瘤的首发体征这种不寻常的表现，该病例尤其值得关注。
