Weusten B L, Franssen H, Wieneke G H, Smout A J
Department of Gastroenterology, University Hospital Utrecht, The Netherlands.
Dig Dis Sci. 1994 Oct;39(10):2074-83. doi: 10.1007/BF02090353.
In order to obtain insight in the generator localization of esophageal evoked potentials, cerebral responses were recorded from 32 scalp electrodes in five healthy volunteers (two male; three female; age 20-30 years), using series of 50 balloon inflations with 15 ml of air. Sequential topographical mapping of waveforms was performed in each subject. Biphasic waveforms were recorded. At Fpz, a positive deflection at 300 and a negative deflection at 465 msec (P300 and N465) were recorded and at Pz, N300 and P465. At Cz the first peak (N270) was slightly earlier than 300 msec. Waveforms were left to right symmetrical. At distal electrodes, biphasic waveforms were recorded (P300 and N465). In four subjects, a gradual phase shift occurred in between the waveforms at midline electrode Cz and the left and right mastoids. Brain mapping showed phase reversals between central negativity and surrounding positivity at about 300 msec, and between central positivity and surrounding negativity at 400-500 msec. Our data suggest the presence of more than one generator in the anterior and dorsal part of the insula and/or dorsal periinsular cortex.
为了深入了解食管诱发电位的发生器定位，对5名健康志愿者（2名男性，3名女性，年龄20 - 30岁）的32个头皮电极记录大脑反应，使用15毫升空气进行50次球囊充气系列操作。对每个受试者进行波形的连续地形图绘制。记录到双相波形。在额极（Fpz），记录到300毫秒时的正向偏转和465毫秒时的负向偏转（P300和N465），在顶极（Pz）记录到N300和P465。在中央点（Cz），第一个峰值（N270）略早于300毫秒。波形左右对称。在远端电极记录到双相波形（P300和N465）。在4名受试者中，中线电极Cz与左右乳突之间的波形出现逐渐的相位偏移。脑图谱显示在约300毫秒时中央负性与周围正性之间以及400 - 500毫秒时中央正性与周围负性之间出现相位反转。我们的数据表明在岛叶前部和背侧部分及/或岛叶周围背侧皮质存在不止一个发生器。
