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1
Meningococcal disease in The Netherlands, 1958-1990: a steady increase in the incidence since 1982 partially caused by new serotypes and subtypes of Neisseria meningitidis.1958 - 1990年荷兰的脑膜炎球菌病：自1982年以来发病率稳步上升，部分原因是脑膜炎奈瑟菌新的血清型和亚型。
Clin Infect Dis. 1993 Feb;16(2):237-46. doi: 10.1093/clind/16.2.237.
2
Serogroups, serotypes and subtypes of Neisseria meningitidis isolated from patients and carriers in Greece.从希腊患者和携带者中分离出的脑膜炎奈瑟菌的血清群、血清型和亚型。
J Med Microbiol. 1993 Jan;38(1):19-22. doi: 10.1099/00222615-38-1-19.
3
Prevalence of maltose-negative Neisseria meningitidis variants during an epidemic period in Spain.西班牙流行期间麦芽糖阴性脑膜炎奈瑟菌变体的流行情况。
J Clin Microbiol. 1982 Jan;15(1):78-81. doi: 10.1128/jcm.15.1.78-81.1982.
4
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Rev Sanid Hig Publica (Madr). 1981 Nov-Dec;55(11-12):1295-308.
5
[Meningococcal meningitis in Spain (1978-1980). I. Epidemiologic studies, serogroups and sensitivity to antimicrobial agents].[西班牙的脑膜炎球菌性脑膜炎（1978 - 1980年）。I. 流行病学研究、血清群及对抗菌药物的敏感性]
Rev Sanid Hig Publica (Madr). 1981 Jul-Aug;55(7-8):831-69.
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Sero- and subtypes of group B meningococci causing invasive infections in Finland in 1976-87.
Scand J Infect Dis. 1989;21(5):527-35. doi: 10.3109/00365548909037881.
7
[Meningococcal meningitis in Spain (1878-1987). VI. Evolution of the proteic subtypes within the serotypes 2 and 15 of Neisseria meningitidis during the epidemic wave].[西班牙的脑膜炎球菌性脑膜炎（1878 - 1987年）。VI. 流行性脑脊髓膜炎奈瑟菌血清型2和15内蛋白质亚型在流行期间的演变]
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8
Effect of outer membrane vesicle vaccine against group B meningococcal disease in Norway.挪威B群脑膜炎球菌病外膜囊泡疫苗的效果
Lancet. 1991 Nov 2;338(8775):1093-6. doi: 10.1016/0140-6736(91)91961-s.
9
An outbreak of serogroup B:15:P1.16 meningococcal disease, Frederiksborg County, Denmark, 1987-9.1987 - 1989年丹麦腓特烈堡郡B群：15：P1.16血清型脑膜炎球菌病暴发
Epidemiol Infect. 1992 Feb;108(1):19-30. doi: 10.1017/s0950268800049463.
10
Serotypes of Neisseria meningitidis isolated from patients in Norway during the first six months of 1978.1978年上半年从挪威患者中分离出的脑膜炎奈瑟菌血清型。
J Clin Microbiol. 1979 Feb;9(2):186-8. doi: 10.1128/jcm.9.2.186-188.1979.

从西班牙患者中分离出的脑膜炎奈瑟菌的血清/亚型分型

Sero/subtyping of Neisseria meningitidis isolated from patients in Spain.

作者信息

Vazquez J A, Marcos C, Berron S

机构信息

Servicio de Bacteriología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.

出版信息

Epidemiol Infect. 1994 Oct;113(2):267-74. doi: 10.1017/s0950268800051694.

DOI:10.1017/s0950268800051694
PMID:7925665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2271546/
Abstract

To know the types of meningococcal strains in Spain, we serotyped and subtyped 743 Neisseria meningitidis isolates recovered between 1990 and 1992 from patients. A great number of serogroup B, serogroup C and non-groupable meningococci reacted with the serotyping reagents while many serogroup C and non-groupable isolates did not react with the serosubtyping reagents (78.2% and 54.8% respectively); only 8.9% of serogroup B meningococci were non-subtypeable (NST). Distribution of serotypes was similar in serogroup C and in non-groupable strains. Isolates showed great variability in antigenic phenotypes (71 in serogroup B, 20 in serogroup C and 25 in non-groupable meningococci). The most frequent antigenic combinations were 4:P1.15 (39.8%) in serogroup B, 2b:NST (55.8%) in serogroup C and 2b:NST (35.6%) in non-groupable meningococci.

摘要

为了解西班牙脑膜炎球菌菌株的类型，我们对1990年至1992年间从患者身上分离出的743株脑膜炎奈瑟菌进行了血清分型和亚型分型。大量B群、C群脑膜炎球菌和不可分型脑膜炎球菌与血清分型试剂发生反应，而许多C群和不可分型分离株不与血清亚型分型试剂发生反应（分别为78.2%和54.8%）；只有8.9%的B群脑膜炎球菌不可进行亚型分型（NST）。C群和不可分型菌株的血清型分布相似。分离株在抗原表型上表现出很大的变异性（B群71种，C群20种，不可分型脑膜炎球菌25种）。最常见的抗原组合是B群中的4:P1.15（39.8%）、C群中的2b:NST（55.8%）和不可分型脑膜炎球菌中的2b:NST（35.6%）。