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1990年至2001年从巴西侵袭性疾病中分离出的脑膜炎奈瑟菌菌株的表型特征

Phenotypic characterization of Neisseria meningitidis strains isolated from invasive disease in Brazil from 1990 to 2001.

作者信息

Lemos Ana Paula S, Brandão Angela P, Gorla Maria Cecília O, Paiva Maria Vaneide, Simonsen Vera, Melles Carmo Elias A

机构信息

Seção de Bacteriologia, Instituto Adolfo Lutz, Avenida Doutor Arnaldo, 355/9 ° andar, Cerqueira César, São Paulo, SP, 01246-902, Brazil.

Fundação Nacional de Saúde, São Paulo, SP, 01220-000, Brazil.

出版信息

J Med Microbiol. 2006 Jun;55(Pt 6):751-757. doi: 10.1099/jmm.0.46451-0.

Abstract

Phenotype characterization of 11 181 invasive Neisseria meningitidis isolates collected in Brazil from 1990 to 2001 was performed. Based on laboratory data, there were 7436 (67 %) serogroup B isolates, 3391 (30 %) C, 236 W135, 51 Y, four 29E, three X, one Z, and 59 of unknown serogroup. Phenotype B : 4,7 : P1.19,15 (54 %) remained the most common during the whole of the 12-year period. Two waves were observed within the serogroup C population: the most frequent phenotype C : 2b : P1.3 (47 %) was replaced after 1998 by non-typable isolates (C : NT : NST) (16 %).

摘要

对1990年至2001年在巴西收集的11181株侵袭性脑膜炎奈瑟菌分离株进行了表型特征分析。根据实验室数据,有7436株(67%)B血清群分离株、3391株(30%)C血清群、236株W135血清群、51株Y血清群、4株29E血清群、3株X血清群、1株Z血清群以及59株血清群不明。在整个12年期间,B:4,7:P1.19,15(54%)表型仍然是最常见的。在C血清群中观察到两个波峰:最常见的C:2b:P1.3(47%)表型在1998年后被不可分型分离株(C:NT:NST)(16%)取代。

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