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采用酶联免疫吸附测定法检测有不良孕产史女性沙眼衣原体抗原、弓形虫(IgM)及人型支原体(IgG)抗体。

Detection of Chlamydia trachomatis antigen & Toxoplasma gondii (IgM) & Mycoplasma hominis (IgG) antibodies by ELISA in women with bad obstetric history.

作者信息

Gogate A, Deodhar L P, Shah P K, Vaidya P

机构信息

Department of Microbiology, LTM Medical College, Bombay.

出版信息

Indian J Med Res. 1994 Jul;100:19-22.

PMID:7927547
Abstract

A total of 365 non pregnant women with bad obstetrics history (BOH) were studied with a control group of 100 women who had delivered full term clinically normal infants. The presence of C. trachomatis antigen and T. gondii (IgM) and M. hominis (IgG) antibodies was assessed by ELISA test. C. trachomatis antigen was detected in 28.2 per cent of women with BOH whereas T. gondii and M. hominis specific antibodies were found in 43.83 and 27.1 per cent respectively, these were highly significant (P < 0.001) in comparison with the control group. In case, facilities for culture are not available then detection of antigen and IgM class of antibodies by ELISA can pinpoint current infection.

摘要

共对365例有不良产科病史(BOH)的非妊娠女性进行了研究,并设立了一个对照组,其中有100名分娩出临床正常足月婴儿的女性。通过酶联免疫吸附测定(ELISA)试验评估沙眼衣原体抗原、弓形虫(IgM)和人型支原体(IgG)抗体的存在情况。在有不良产科病史的女性中,28.2%检测到沙眼衣原体抗原,而分别有43.83%和27.1%的女性检测到弓形虫和人型支原体特异性抗体,与对照组相比,这些差异具有高度显著性(P < 0.001)。如果没有培养设施,那么通过ELISA检测抗原和IgM类抗体可以确定当前感染情况。

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