K99菌毛与N-糖基化神经节苷脂GM3受体的多价结合。
Multivalent binding of K99 fimbriae to the N-glycolyl-GM3 ganglioside receptor.
作者信息
Willemsen P T, de Graaf F K
机构信息
Department of Molecular Microbiology, Faculty of Biology, Vrije Universiteit, Amsterdam, The Netherlands.
出版信息
Infect Immun. 1993 Oct;61(10):4518-22. doi: 10.1128/iai.61.10.4518-4522.1993.
Abstract
The ganglioside N-glycolyl-GM3 binds laterally at numerous positions to K99 fimbriae, as shown by electron microscopic detection and erythrocyte-binding activity. The data demonstrate the multivalent nature of K99 fimbriae with respect to their receptor-binding sites.
摘要
神经节苷脂N-羟乙酰神经氨酸-GM3通过电子显微镜检测和红细胞结合活性表明，在多个位置横向结合于K99菌毛。这些数据证明了K99菌毛在其受体结合位点方面具有多价性质。
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