Heffernan E J, Wu L, Louie J, Okamoto S, Fierer J, Guiney D G
Department of Medicine, University of California, San Diego.
Infect Immun. 1994 Nov;62(11):5183-6. doi: 10.1128/iai.62.11.5183-5186.1994.
Virulence-associated phenotypes of an outer membrane protein gene family of members of the family Enterobacteriaceae were compared by means of pBR322 constructs transformed into Escherichia coli HB101.rck (Salmonella typhimurium) and ail (Yersinia enterocolitica) promote serum resistance and eukaryotic cell invasion, properties not shared by other members of the gene family, pagC, ompX, and lom.
通过转化到大肠杆菌HB101中的pBR322构建体,比较了肠杆菌科成员的一个外膜蛋白基因家族的毒力相关表型。鼠伤寒沙门氏菌的rck和小肠结肠炎耶尔森氏菌的ail可促进血清抗性和真核细胞侵袭,这些特性是该基因家族的其他成员pagC、ompX和lom所不具备的。