硫代己糖酸α，一种由“塞贝基亚”属LL-14E605菌株产生的新型抗生素。III. 结构解析。
Glycothiohexide alpha, a novel antibiotic produced by "Sebekia" sp., LL-14E605. III. Structural elucidation.
作者信息
Northcote P T, Siegel M, Borders D B, Lee M D
机构信息
Natural Products Research Section, American Cyanamid Company, Pearl River, New York 10965.
出版信息
J Antibiot (Tokyo). 1994 Aug;47(8):901-8. doi: 10.7164/antibiotics.47.901.
PMID:7928677
Abstract
The chemical structure of a novel thiopeptide antibiotic, glycothiohexide alpha (1), isolated from the fermentation broth of a "Sebekia" species was determined based on extensive 2D NMR studies, as well as, IR, UV, and mass spectral data. The chemical structure of glycothiohexide alpha is closely related to nosiheptide (3) and antibiotic S-54832A.
摘要
从一种“塞贝克氏菌”属物种的发酵液中分离出的新型硫肽抗生素——甘氨硫己肽α（1）的化学结构，是基于广泛的二维核磁共振研究以及红外、紫外和质谱数据确定的。甘氨硫己肽α的化学结构与诺西肽（3）和抗生素S - 54832A密切相关。
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