Sadé J, Fuchs C
Ear Research Laboratory, Sackler School of Medicine, Tel Avi University, Ramat Aviv, Israel.
J Laryngol Otol. 1994 Jul;108(7):541-4. doi: 10.1017/s0022215100127380.
The records of 148 adults (aged 14 years and older) presenting previously untreated aural cholesteatomas are analysed with particular emphasis on ossicular destruction and other bony lesions in the middle ear. The findings are compared with those obtained in an earlier study of 63 children (aged 13 years and younger), also with untreated cholesteatomas. The rate of stapes and malleus destruction was similar in adults and children. The rate of incus destruction was significantly higher in adults. Semicircular fistulas as well as facial paralysis were also more prevalent amongst adults. Therefore, the notion of childhood cholesteatoma aggressiveness cannot be related to its effect on these bony structures. It may stem from its higher recurrence rate and from the more troublesome post-operative mastoid cavities, which are often larger in children than in adults.
分析了148例（年龄14岁及以上）此前未经治疗的中耳胆脂瘤成人患者的记录，特别关注听骨破坏及中耳的其他骨质病变。将这些结果与早期一项针对63例（年龄13岁及以下）同样未经治疗的中耳胆脂瘤儿童患者的研究结果进行比较。成人和儿童的镫骨及锤骨破坏率相似。砧骨破坏率在成人中显著更高。成人中半规管瘘管和面神经麻痹也更常见。因此，儿童中耳胆脂瘤的侵袭性概念与其对这些骨质结构的影响无关。它可能源于其更高的复发率以及术后乳突腔更棘手的问题，儿童的乳突腔通常比成人的更大。
