Coleston D M, Chronicle E, Ruddock K H, Kennard C
Academic Unit of Neuroscience, Charing Cross and Westminister Medical School, London, UK.
J Neurol Neurosurg Psychiatry. 1994 Oct;57(10):1208-11. doi: 10.1136/jnnp.57.10.1208.
This paper examines spatial and temporal processing in migraineurs (diagnosed according to International Headache Society criteria, 1988), using psychophysical tests that measure spatial and temporal responses. These tests are considered to specifically assess precortical mechanisms. Results suggest precortical dysfunction for processing of spatial and temporal visual stimuli in 11 migraineurs with visual aura and 13 migraineurs without aura; the two groups could not be distinguished. As precortical dysfunction seems to be common to both groups of patients, it is suggested that symptoms that are experienced by both groups, such as blurring of vision and photophobia, may have their basis at a precortical level.
本文采用测量空间和时间反应的心理物理学测试，研究偏头痛患者（根据1988年国际头痛协会标准诊断）的空间和时间处理能力。这些测试被认为可专门评估皮层下机制。结果表明，11名有视觉先兆的偏头痛患者和13名无先兆的偏头痛患者在处理空间和时间视觉刺激方面存在皮层下功能障碍；两组之间无法区分。由于皮层下功能障碍似乎在两组患者中都很常见，因此有人提出，两组患者都经历的症状，如视力模糊和畏光，可能在皮层下水平就有其根源。
