Skidmore J A, Allen W R, Heap R B
Camel Reproduction Laboratory, Nakhlee, Dubai, United Arab Emirates.
J Reprod Fertil. 1994 Jul;101(2):363-7. doi: 10.1530/jrf.0.1010363.
The ability of the embryonic tissues of the dromedary camel (Camelus dromedarius) to synthesize oestrogens in vitro was studied in 15 conceptuses recovered by non-surgical uterine lavage between 10 and 33 days after ovulation. Definitive evidence for strong aromatase activity with synthesis of considerable quantities of oestrogens was obtained at all stages when conceptus tissues were incubated with [3H]androstenedione. A high proportion of the oestrogens was in the form of oestradiol, which contrasts to the higher ratio of oestrone:oestradiol in the oestrogens synthesized by embryonic tissues of horses and pigs. Biopsies of endometrial tissue recovered from pregnant and nonpregnant camels showed great ability to conjugate both oestradiol and oestrone when incubated with tritium-labelled forms of these two hormones.
在排卵后10至33天通过非手术子宫灌洗回收的15个孕体中,研究了单峰骆驼(骆驼属单峰驼)胚胎组织在体外合成雌激素的能力。当孕体组织与[3H]雄烯二酮一起孵育时,在所有阶段都获得了具有大量雌激素合成的强芳香化酶活性的确切证据。大部分雌激素以雌二醇的形式存在,这与马和猪的胚胎组织合成的雌激素中雌酮:雌二醇的比例较高形成对比。从怀孕和未怀孕的骆驼中回收的子宫内膜组织活检显示,当与这两种激素的氚标记形式一起孵育时,具有很强的结合雌二醇和雌酮的能力。