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将苯丙胺作为一种减少伤害的措施来开具处方是否合理?

Is the prescription of amphetamine justified as a harm reduction measure?

作者信息

Fleming P M, Roberts D

机构信息

Drug Advice Centre, Cosham, Portsmouth, Hampshire.

出版信息

J R Soc Health. 1994 Jun;114(3):127-31. doi: 10.1177/146642409411400303.

DOI:10.1177/146642409411400303
PMID:7932481
Abstract

Although amphetamine is the most widely illicitly used drug in the United Kingdom after cannabis, relatively few problematic users present to treatment agencies. Injecting amphetamine users are a high risk group as far as HIV transmission is concerned. This paper reviews the first 3 years' operation of an oral amphetamine prescribing programme for injecting users. Over half the subjects ceased injecting, and there was a considerable reduction in injecting by the remainder. 85% had not used or shared injecting equipment during the programme. However, subjects reported still using street amphetamine and offending, although at a lower rate than previously. There was little change in sexual practices. There was an increase in primary amphetamine users presenting for treatment. There is a case to be made that closely controlled and monitored programmes such as this can be justified on harm reduction grounds. A number of issues concerned with amphetamine prescribing are discussed.

摘要

尽管在英国,苯丙胺是继大麻之后使用最为广泛的非法药物,但到治疗机构寻求帮助的问题使用者相对较少。就艾滋病毒传播而言,注射用苯丙胺使用者是高危群体。本文回顾了一项针对注射使用者的口服苯丙胺处方项目头三年的运行情况。超过半数的受试者停止了注射,其余受试者的注射行为也大幅减少。85%的受试者在项目期间未使用或共用注射设备。然而,受试者报告仍在使用街头苯丙胺并存在犯罪行为,尽管发生率低于此前。性行为方面几乎没有变化。前来接受治疗的原发性苯丙胺使用者有所增加。有理由认为,像这样受到严格控制和监测的项目基于减少伤害的理由是合理的。文中还讨论了一些与苯丙胺处方相关的问题。

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