Boo N Y, Oakes M, Lye M S, Said H
Department of Pediatrics, Faculty of Medicine, National University of Malaysia, Kuala Lumpur.
J Trop Pediatr. 1994 Aug;40(4):194-7. doi: 10.1093/tropej/40.4.194.
A study of 128 jaundiced term neonates showed that 28 (22 per cent) had hearing loss based on brain stem-evoked response. There was no significant difference in the percentage of neonates with hearing loss between those with peak serum bilirubin levels of less than 340 mumol/l (16 per cent) and those with hyperbilirubinaemia > 339 mumol/l (33 per cent) (P = 0.11). Logistic regression analysis showed that severe jaundice which required exchange transfusion and earlier age of onset of hyperbilirubinaemia were statistically significant risk factors associated with hearing loss (P = 0.038 and P = 0.012, respectively).
一项针对128名足月黄疸新生儿的研究表明，基于脑干听觉诱发电位，有28名（22%）存在听力损失。血清胆红素峰值水平低于340μmol/l的新生儿中听力损失的比例（16%）与高胆红素血症>339μmol/l的新生儿（33%）之间无显著差异（P = 0.11）。逻辑回归分析表明，需要换血治疗的重度黄疸以及高胆红素血症的较早发病年龄是与听力损失相关的具有统计学意义的危险因素（分别为P = 0.038和P = 0.012）。
