Landau E H, Churchill B M, Jayanthi V R, Gilmour R F, Steckler R E, McLorie G A, Khoury A E
Department of Surgery, Hospital for Sick Children, Toronto, Ontario, Canada.
J Urol. 1994 Nov;152(5 Pt 1):1578-81. doi: 10.1016/s0022-5347(17)32479-5.
Assessment of bladder storage function requires an accurate measure of bladder capacity and pressure. Pressure specific bladder volume is the volume that a bladder can accommodate at a specific pressure. A total of 21 consecutive children with neurogenic bladders who were candidates for bladder augmentation based on standard clinical criteria (upper urinary tract deterioration, incontinence and infection) was studied to determine the efficacy of pressure specific bladder volume as a measure of bladder dysfunction. Urodynamic indexes were compared to previously established nomograms. All 21 patients had bladder volumes at pressures of 30 cm. water or less, which decreased below the 5th percentile as determined by the nomogram. In 7 patients (33%) normal total bladder capacity was achieved at the expense of elevated storage pressures. Pressure specific bladder volume provides a better measure of bladder storage function than total bladder capacity because it relates volume to intravesical pressure, does not rely on a subjective end point to bladder filling, and is objective and reproducible.
膀胱储尿功能的评估需要准确测量膀胱容量和压力。压力特异性膀胱容量是指膀胱在特定压力下能够容纳的容量。本研究共纳入了21例连续的神经源性膀胱患儿，这些患儿根据标准临床标准（上尿路恶化、尿失禁和感染）符合膀胱扩大术的指征，旨在确定压力特异性膀胱容量作为膀胱功能障碍指标的有效性。将尿动力学指标与先前建立的列线图进行比较。所有21例患者在30厘米水柱或更低压力下的膀胱容量均低于列线图确定的第5百分位数。7例患者（33%）以储存压力升高为代价实现了正常的膀胱总容量。压力特异性膀胱容量比膀胱总容量能更好地评估膀胱储尿功能，因为它将容量与膀胱内压相关联，不依赖于膀胱充盈的主观终点，且客观且可重复。
