Suleĭmanov S D
Med Parazitol (Mosk). 1994 Apr-Jun(2):8-10.
Three antimalarial treatment regimens by the complete standard WHO tests were examined in 105 Plasmodium falciparum-infected patients who were nonimmune newcomers treated at the Russian hospital in Luanda in 1991-1992, 61% showed chloroquine resistance and 40% fansidar resistance. All 59 patients with high rates of parasitemia were successfully cured with quinine in combination with tetracycline. Thick, if required thin, blood smears were microscopically examined. The findings suggest that Fansidar should be a drug of first-line therapy in Angola, though in the neighbouring countries quinine continues preserving its efficacy, but there is a delayed elimination of the parasites within 7 days of initiation of the therapy, making it necessary to prolong therapy with this drug up to 10 days.
1991年至1992年期间，在罗安达的俄罗斯医院对105名感染恶性疟原虫的非免疫新患者进行了三项符合世界卫生组织完整标准测试的抗疟治疗方案检查，61%的患者显示对氯喹耐药，40%的患者显示对Fansidar耐药。所有59名寄生虫血症率高的患者均用奎宁联合四环素成功治愈。必要时进行厚血涂片检查，如需要还进行薄血涂片显微镜检查。研究结果表明，在安哥拉，Fansidar应作为一线治疗药物，尽管在邻国奎宁仍保持其疗效，但在治疗开始后7天内寄生虫清除延迟，因此有必要将该药物的治疗延长至10天。
