利福平与氯霉素对紫外线损伤的大肠杆菌B/r WP2 thy trp中DNA复制的影响
Rifampicin and chloramphenicol effects on DNA replication in ultraviolet-damaged Escherichia coli B/r WP2 thy trp.
作者信息
Doudney C O
出版信息
Biochim Biophys Acta. 1976 Dec 13;454(3):389-96. doi: 10.1016/0005-2787(76)90265-3.
PMID:793626
Abstract
The antibiotic rifampicin, which blocks specifically RNA synthesis, limited DNA replication in Escherichia coli strain B/r WP2 thy trp after an increase of about 50%, when added to the incubation medium at the time of replication initiation after ultraviolet fluences of 20 J/m2...
摘要
抗生素利福平能特异性阻断RNA合成，在大肠杆菌B/r WP2 thy trp菌株中，当在紫外线照射量为20 J/m²后复制起始时添加到孵育培养基中，利福平会在DNA复制增加约50%后对其进行限制……
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