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快速率经颅磁刺激与半球语言优势:在癫痫中的效用与安全性

Rapid-rate transcranial magnetic stimulation and hemispheric language dominance: usefulness and safety in epilepsy.

作者信息

Michelucci R, Valzania F, Passarelli D, Santangelo M, Rizzi R, Buzzi A M, Tempestini A, Tassinari C A

机构信息

Department of Neurology, University of Bologna, Bellaria Hospital, Italy.

出版信息

Neurology. 1994 Sep;44(9):1697-700. doi: 10.1212/wnl.44.9.1697.

DOI:10.1212/wnl.44.9.1697
PMID:7936299
Abstract

We performed rapid-rate transcranial magnetic stimulation (r-TMS) in 14 epileptic patients, using a coil centered over nine different positions on each side of the scalp and while the subjects counted aloud. We obtained lateralized speech arrest, concordant with the site of manual preference, in only seven patients. There was transitory homonymous hemianopia (one patient), brief jerking of one arm (two patients), and affective (crying) reaction (three patients) after the end of a train of stimuli. In our experience, r-TMS is not as sensitive as previously reported for determination of hemispheric language dominance and may have undesirable side effects.

摘要

我们对14名癫痫患者进行了快速重复经颅磁刺激(r-TMS),使用一个线圈置于头皮每侧九个不同位置的上方,同时让受试者大声计数。我们仅在7名患者中获得了与利手部位一致的言语停顿。在一系列刺激结束后,出现了短暂性同向性偏盲(1例患者)、一侧手臂短暂抽搐(2例患者)和情感反应(哭泣,3例患者)。根据我们的经验,r-TMS在确定半球语言优势方面不如先前报道的那样敏感,并且可能有不良副作用。

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