Cariello N F
Glaxo, Inc., Drug Safety Assessment, Research Triangle Park, NC 27709.
Nucleic Acids Res. 1994 Sep;22(17):3547-8.
A computerized database containing DNA sequence information regarding human HPRT mutants has been created. The database itself is in the dBASE format and contains information on about 1500 mutants. In addition, an IBM PC compatible software package to analyze the information in the database has been developed. Both the database and software are freely available via the Internet.
一个包含人类次黄嘌呤磷酸核糖转移酶(HPRT)突变体DNA序列信息的计算机化数据库已经建立。该数据库本身采用dBASE格式,包含约1500个突变体的信息。此外,还开发了一个用于分析数据库中信息的IBM个人计算机兼容软件包。数据库和软件均可通过互联网免费获取。