人类肿瘤和细胞系中p53基因体细胞突变数据库。
Database of p53 gene somatic mutations in human tumors and cell lines.
作者信息
Hollstein M, Rice K, Greenblatt M S, Soussi T, Fuchs R, Sørlie T, Hovig E, Smith-Sørensen B, Montesano R, Harris C C
机构信息
German Cancer Research Center, Heidelberg.
出版信息
Nucleic Acids Res. 1994 Sep;22(17):3551-5.
Abstract
A data base is described in which over 2,500 mutations in the p53 gene of human tumors and tumor cell lines are compiled from a systematic search of reports published before 1 January 1994. Data from 1994 are being added intermittently, with a systematic search and update scheduled for December, 1994. The compilation has been deposited with the EMBL Data Library and is available in electronic form free of charge. This report contains a rationale for the compilation, a brief summary of the major findings and a description of the data base.
摘要
本文描述了一个数据库，该数据库通过对1994年1月1日前发表的报告进行系统检索，汇集了人类肿瘤和肿瘤细胞系p53基因的2500多个突变。1994年的数据正在陆续添加，计划于1994年12月进行系统检索和更新。该汇编已存入欧洲分子生物学实验室数据库，并以电子形式免费提供。本报告包含汇编的基本原理、主要发现的简要总结以及数据库的描述。
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