基因定位的渐近理论。
Asymptotic theory for gene mapping.
作者信息
Kong A, Wright F
机构信息
Department of Statistics, University of Chicago, IL 60637.
出版信息
Proc Natl Acad Sci U S A. 1994 Oct 11;91(21):9705-9. doi: 10.1073/pnas.91.21.9705.
Abstract
In genetic linkage mapping, the precision of the location estimate depends on both the number of individuals and the number of markers. Convergence rates and limit laws are established for several situations in which the number of markers depends on the sample size. Practical implications of the results are discussed.
摘要
在基因连锁图谱分析中，位置估计的精度取决于个体数量和标记数量。针对标记数量取决于样本量的几种情况，建立了收敛速率和极限定律。并讨论了结果的实际意义。
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