Schulz M, Schmoldt A
Drug Information Center, ABDA, Eschborn.
Pharmazie. 1994 Aug;49(8):614.
We report on a severe intoxication with the tricyclic antidepressant dothiepin. A treatment with a continuous infusion of physostigmine was successful and improved the ventricular arrhythmia. Dothiepin and its active metabolites were determined in plasma and urine by HPLC.