Hofstad B, Vatn M, Larsen S, Osnes M
Medical Dept, Ullevål Hospital, Oslo, Norway.
Scand J Gastroenterol. 1994 Jul;29(7):640-5. doi: 10.3109/00365529409092485.
Colonoscopic 1-year control of polyps of less than 10 mm left in situ was carried out in 103 (89%) of 116 originally examined patients.
Analysis showed an 85% recovery: 91% and 81% for polyps of 5-9 mm and < 5 mm, respectively. The recovery was significantly related to size and localization, whereas the growth rate was inversely correlated to the originally measured diameter. A linear relationship was demonstrated between anus-to-polyp distances 1 year apart, with a normalized agreement index of 0.70. In only 1 of 189 polyps, an increase of diameter to > 10 mm was demonstrated. The 79 new polyps in 52 (50%) of the patients were significantly smaller, more often right-sided, and related to multiplicity of polyps at the initial examination but not to growth of recovered polyps or cleansing status.
An acceptable recovery and growth rate of polyps < 10 mm seems to justify the continuation of the study for the remaining 2 years.
对116例最初接受检查的患者中的103例（89%）进行了结肠镜检查，对直径小于10mm的原位息肉进行了为期1年的监测。
分析显示息肉的回收率为85%：5-9mm和小于5mm的息肉回收率分别为91%和81%。回收率与息肉大小和位置显著相关，而生长率与最初测量的直径呈负相关。相隔1年的肛门到息肉的距离之间呈现线性关系，标准化一致性指数为0.70。在189个息肉中，仅有1个息肉直径增大至大于10mm。52例（50%）患者中的79个新发息肉明显更小，更多位于右侧，且与初次检查时息肉的多发性有关，但与已恢复息肉的生长或清洁状态无关。
直径小于10mm的息肉具有可接受的回收率和生长率，这似乎为继续进行为期2年的后续研究提供了依据。
