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确定D1细胞为人类胰多肽（HPP）的来源。

Identification of the D1-cell as the source of human pancreatic polypeptide (HPP).

作者信息

Heitz P, Polak J M, Bloom S R, Pearse A G

出版信息

Gut. 1976 Oct;17(10):755-8. doi: 10.1136/gut.17.10.755.

DOI:10.1136/gut.17.10.755
PMID:793954
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1411184/
Abstract

Immunoperoxidase positive HPP-producing cells have been examined ultrastructurally using the serial semithin-thin section technique. The features of the HPP cells were found to be identical with those of the previously described D1-cell. The D1-cells are scattered throughout the exocrine parenchyma and occur to a minor extent in the islets.

摘要

利用连续半薄-超薄切片技术，对免疫过氧化物酶阳性的产生高血糖素的细胞进行了超微结构检查。发现高血糖素细胞的特征与先前描述的D1细胞相同。D1细胞散布于整个外分泌实质，在胰岛中也有少量存在。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1d7/1411184/993607dccaeb/gut00491-0021-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1d7/1411184/d48b20c57adc/gut00491-0020-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1d7/1411184/993607dccaeb/gut00491-0021-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1d7/1411184/d48b20c57adc/gut00491-0020-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1d7/1411184/993607dccaeb/gut00491-0021-a.jpg

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引用本文的文献

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本文引用的文献

1
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2
Localization of APP, a postulated new hormone, to a pancreatic endocrine cell type.假定的新激素APP在胰腺一种内分泌细胞类型中的定位。
Histochemistry. 1974;42(4):377-82. doi: 10.1007/BF00492685.
3
Studies of the distribution of a new avian pancreatic polypeptide and insulin among birds, reptiles, amphibians and mammals.一种新型禽胰多肽和胰岛素在鸟类、爬行动物、两栖动物及哺乳动物中的分布研究。
J R Coll Physicians Lond. 1980 Jan;14(1):51-7.
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Correlative immunocytochemical and electron microscopic studies: identification of (entero)glucagon- somatostatin- and pancreatic polypeptide-like-containing cells in the human colon.相关免疫细胞化学和电子显微镜研究：人结肠中含胰高血糖素-生长抑素-和胰多肽样细胞的鉴定。
Histochemistry. 1981;71(1):67-80. doi: 10.1007/BF00592571.
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The ultrastructural identity of pancreatic polypeptide cells in chicks.
Histochemistry. 1980;65(3):261-7. doi: 10.1007/BF00493175.
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Types of endocrine cells in the human colon and rectum.人类结肠和直肠中的内分泌细胞类型。
Cell Tissue Res. 1978 Sep 5;192(2):227-40. doi: 10.1007/BF00220741.
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Immunohistochemical identification and localization of pancreatic polypeptide cells in the pancreas and gastrointestinal tract of the human fetus and adult man.
Cell Tissue Res. 1978 Apr 17;188(2):251-7. doi: 10.1007/BF00222634.
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Mechanism and specificity of increased amylase/creatinine clearance ratio in pancreatitis.胰腺炎中淀粉酶/肌酐清除率升高的机制及特异性。
Gut. 1977 Sep;18(9):703-8. doi: 10.1136/gut.18.9.703.
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Pancreatic apudomas.胰腺APUD瘤
World J Surg. 1979 Sep 20;3(5):587-95. doi: 10.1007/BF01654765.
10
Localization of pancreatic polypeptide cells in a limited lobe of the human neonate pancreas: remnant of the ventral primordium?
Cell Tissue Res. 1979 Sep 1;200(3):359-66. doi: 10.1007/BF00234848.
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4
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5
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J Biol Chem. 1975 Dec 25;250(24):9369-76.
7
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