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从奶牛乳腺分离出的链球菌属中的大环内酯-林可酰胺类耐药决定因子

Macrolide-lincosamide resistance determinants in streptococcal species isolated from the bovine mammary gland.

作者信息

Roberts M C, Brown M B

机构信息

Department of Pathobiology, University of Washington, Seattle 98195.

出版信息

Vet Microbiol. 1994 Jun;40(3-4):253-61. doi: 10.1016/0378-1135(94)90114-7.

Abstract

Seventy one streptococci isolated from dairy cows with clinical mastitis were tested for erythromycin and lincomycin susceptibility. Ten isolates (7.1%) were resistant to erythromycin and/or lincomycin and seven were constitutive and three were inducibly resistant. Nine of the isolates hybridized with one or more of the Erm probes tested and eight isolates gave PCR products with rRNA methylase primers. The Erm determinants were transferable at frequency of 10(-5) to 10(-6) per recipient.

摘要

对从患有临床乳腺炎的奶牛中分离出的71株链球菌进行了红霉素和林可霉素敏感性测试。10株分离株(7.1%)对红霉素和/或林可霉素耐药,其中7株为组成型耐药,3株为诱导型耐药。9株分离株与所测试的一种或多种Erm探针杂交,8株分离株用rRNA甲基化酶引物得到PCR产物。Erm决定簇以每受体10^(-5)至10^(-6)的频率可转移。

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